On May 31th is World no tobacco day, in which UN launches an awareness campaign about the fundamental role of lung in people’s general health, as well as the harmful effect of tobacco on lungs that can go from respiratory diseases to cancer.
In agreement with the American Cancer Society, 13% of all cancer is lung cancer, and by 2019 there will be 142,670 new deaths due to this condition. Lung cancer can be classified into small cells lung cancer (SCLC) and non-small cells lung cancer (NSCLC) the latter being the most common with an 80% to 85% prevalence. NSCLC can be sub classified into three subtypes: Adenocarcinoma, squamous cell carcinoma and large cell carcinoma.
Tobacco smoke es the most recognize risk factor for the development of lung adenocarcinoma, many research centers keep studying lung cells normal process affected by the tobacco smoke to fully understand the mechanisms of carcinogenic process and continue with the search of new treatments. A study release in 2018 by Stueve et al. Lung transplants remnants cells were exposed to cigarette smoke condensates (CSC). It was found that CSC increases the risk of developing lung adenocarcinoma by affecting molecular factors like TGF-β and AhR who oversee regulation of proteins like adhesins, extracellular matrix components, essential for the normal tissue repair after any injury in lungs.
As we mentioned before, lung cancer is one of the most common cancer, the search for better medicines for its treatment is crucial. Here in Althian a protocol for patients with lung adenocarcinoma, specifically for long time smokers is carried out, thus, don’t hesitate to contact us for further details and information.